Paper vs. eCRF
There are specific advantages and disadvantages for each medium, that can be used for a study
| Advantages | Disadvantages | |
|---|---|---|
| Paper | 
        Easy data entry No training needed No computer expertise needed Low expenditure for programming Marketing effect due to presence at the doctor  | 
      
        Printing & postage costs Delivery time Implausibilities lead to paper queries with additional running time  | 
    
| Electronic | 
        Directly checked for plausibility Less queries needed Study progress known Latest data available No training due to intuitive user guidance  | 
      
        Higher expenditure for programming Selects doctors by digitization status  | 
    
| Hybride | 
        
        All advantages of paper studies All advantages of electronic studies Identical layout paper & eCRF No selection of doctors  | 
      High overall expenditure | 
